Metabolite screening

Professor Dalton and Dr Turner have supported the metabolic service in Evelina Children’s Hospital and its pathology laboratories, introducing a wide range of tests performed using mass spectrometry. They have developed these tests, migrating most of them onto robust, simple, and safer dried bloodspots.

SpOtOn’s innovative technology enables these tests to be performed much more cost-effectively and turned around more rapidly than alternative methods.

Selected tests offered on either bloodspot or plasma (except where indicated) include:

  • 3-o-methyl dopa
  • Acylcarnitines
  • Amino acids (on urine as well)
  • Biotinidase
  • Creatine/ Guanidinoacetate (on plasma or urine only)
  • Organic acids, selected ones only (also available on urine)
  • Pyrimidine
  • Sialic acid
  • Sulpho-cysteines (on urine only)
  • White Cell Cystine (on whole blood only)


SpOtOn offers these services both directly to clinicians, as well as supporting laboratories with their more specialist requirements in this area.

Contact us to see how we may be able to assist you, or to send us a sample.